At the same site, “Lakefront” and “wind” are used synonymously and frequently.
I have to wonder how many of those comments were based on the 2002 and 2004 editions of the race. Those are the only ones I'm aware of where the wind was a significant negative factor. For a nearly 30 year history, two editions being affected so significantly by a headwind on this type of course doesn't seem like all that bad odds.
I truly believe that Lakefront is a great course for running a fast time. Yes, you put yourself at the mercy of the weather but you do when running any marathon, especially ones run on point to point courses. If the conditions are right, though, I think Lakefront can be as fast as anything out there.