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Again, this comes back to the question of whether they would offer a benefit as HGH and steroids do.
They must as they allow a man missing half of his legs to run that fast. It is unnatural (even within the context of the current expanse of what is allowable) and therefore unequal with what the competition is reasonably allowed.
Certainly, and yet there is ostensibly no valid basis for comparison.
The drag and spring of the prosthetic could be measured against the drag and spring of athletes of similar ability.
Which takes in more than a little leap of faith and assumption.
If outside of a reasonable percentile, then it would be evidence of aid. Again, I'm not sure this would still be fair and, the more I debate and think over this, the more I'm convinced that the prosthetics do provide obvious aid and should not be allowed. Another factor to consider is that his ratio of hard working muscles to more lightly working muscles, which might affect blood lactate levels and a 400 meter runner's ability to maintain speed over the final 100, would be lower.
Certainly, though it is still incredibly specious. Nervous system signals and blood travels a shorter distance yet to fewer end-points in his lower extremities than with an able-bodied athlete. However, only so much bulk, mitochondria, and capillary beds can (naturally) be built onto the remaining leg muscles. Muscles are loaded differently in the absence of the calf sheath and the rest and a prosthetic has significantly altered recovery and resiliency in comparison with a natural leg. It is like the argument used against public school segregation, significant separation is inherently unequal.