Another thing to consider. If taking one supplement a day is enough to balance a deficiency that you have, spreading out the supplementation could cause an overdosage. For example, I have had iron deficiency problems in the past. I take one iron supplement a day and, along with dietary changes, this has led to sustaining my iron levels in an appropriate range. If I were to take a supplement that required me to take it 3 times a day, even if the total daily dosage was the same, it would be possible that I would end up overdosing on iron, which can be just as dangerous as low iron levels. FWIW, my doctors have been guiding my supplementation from the very beginning and have been telling me exactly what to take and how to take it. I have to believe they know what they are doing and the results I have seen support this belief.
Out of curiosity, I know there are at least a couple of medical professionals on this forum. I’d be interested to hear their thoughts on this whole topic.